Dicarboxylic acids and derivatives
Selleck Chemical LLC GlyH-101
GlyH-101 is a selective and reversible CFTR inhibitor with Ki of 4 3 M
Selleck Chemical LLC CUDC-101 S1194-10mM/1mL
CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
Medchemexpress LLC Vnt-101 | 2894060-67-2 | 456.41 | C21H23F3N2O6 | 10 MG
VNT-101 is a small-molecule, orally active inhibitor of influenza A virus nucleoprotein (NP) oligomerization. It disrupts NP-NP protein-protein interactions to destabilize the viral ribonucleoprotein complex and has been used in vitro and in vivo to study antiviral activity across multiple influenza A subtypes.
- Disrupts nucleoprotein oligomerization to inhibit viral replication.
- Orally bioavailable small molecule suitable for in vivo studies.
- Demonstrated activity against multiple influenza A subtypes.
- Molecular weight 456.41 and molecular formula C21H23F3N2O6.
- CAS number 2894060-67-2 for substance identification.
- Supplied as a solid for research use with supporting characterization data.
Medchemexpress LLC Ethyl Lauroyl Argina 1g
Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative[1]
![Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236923.png-250.jpg)
Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG
LEI-101 hydrochloride is a potent, selective, orally bioavailable cannabinoid CB2 receptor agonist supplied for research use. It demonstrates strong functional activity at human CB2 receptors with substantially lower affinity for CB1 and minimal hERG binding, suitable for in vitro and in vivo pharmacology studies.
- Purity 99.4%.
- Reported activity pEC50 = 8 for human CB2.
- Approximately 100-fold selectivity for CB2 over CB1.
- Low hERG interaction (pKi < 4).
- Soluble in DMSO; available as dry powder and 10 mM solution in DMSO.
- Intended for research use only; not for human or clinical use.
TARGETMOL CHEMICALS INC KHS 101 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation. Purity 98%
Medchemexpress LLC FITC-labeled ODN 1018 sodium | 98.7% | 8,171.00 Da | 10 MG
FITC-labeled ODN 1018 sodium is an FITC-conjugated CpG oligodeoxynucleotide that functions as a Toll-like receptor 9 (TLR9) agonist. Supplied as the sodium salt, it is used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy or flow cytometry. For research use only.
- FITC label with excitation 495 nm and emission 520 nm.
- CpG oligodeoxynucleotide sequence: d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A).
- Molecular weight approximately 8,171 Da.
- Purity 98.7% as supplied.
- Sodium salt form.
- Available in 1 mg, 5 mg, and 10 mg sizes; larger sizes available by quote.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻¹ | C29H58NO8P | 100 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a phosphatidylethanolamine derivative bearing two lauroyl (C12:0) acyl chains. It is a research-grade lipid commonly used for liposome formulation and membrane model studies; typical properties include a molecular weight of 579.75 g·mol⁻¹ and high purity (98.0%).
- Phosphatidylethanolamine lipid with two lauroyl (C12:0) chains.
- Suitable for liposome synthesis and membrane model studies.
- High purity (98.0%) for research applications.
- Molecular formula C29H58NO8P and molecular weight 579.75 g·mol⁻¹.
Selleck Chemical LLC CUDC-101 S1194-1g
CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
Apexbio Technology LLC LOXO-101 1223405-08-0 25mg
LOXO-101 (CAS 1223405-08-0) is a potent and selective inhibitor of the tropomyosin receptor kinase (TRK) family demonstrating low nanomolar inhibitory activity across all TRK isoforms LOXO-101 disrupts signaling mediated by neurotrophin receptors which are critical for neuronal development and survival In kinase profiling LOXO-101 exhibited minimal off-target activity with significant inhibition observed only for TNK2 (IC50 576 nM) and did not display hERG inhibition or QT prolongation effects In vivo studies revealed dose-dependent tumor growth suppression in xenograft models Clinically LOXO-101 has been evaluated for safety and pharmacokinetics and induced rapid tumor regression in a TRK fusion-positive patient highlighting its utility in studying TRK-driven malignancies
